سعر تايزيل Tizyl‏ 4مجم 10 اقراص 2026

Tizanidine 4 mg tablets, box of 10 (October Pharma > Pharmagin Egypt); centrally acting alpha-2 adrenergic agonist muscle relaxant.

• Most common (>10%): dry mouth, somnolence, asthenia and dizziness.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Concomitant strong CYP1A2 inhibitors (e.g. fluvoxamine, ciprofloxacin).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• History of hypersensitivity to tizanidine or tablet ingredients (anaphylaxis, angioedema).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypotension and syncope; monitor especially with antihypertensives; not recommended with other alpha-2 agonists.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Hepatocellular liver injury may occur; monitor aminotransferases at baseline and 1 month after maximum dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Sedation, hallucinations/psychotic-like symptoms, hypersensitivity reactions and withdrawal reactions on abrupt stop.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Strong CYP1A2 inhibitors (fluvoxamine, ciprofloxacin)Contraindicated: marked hypotension, drowsiness and psychomotor impairment.DailyMed (U.S. National Library of Medicine)
• Moderate/weak CYP1A2 inhibitors (e.g. zileuton, amiodarone, cimetidine, famotidine, acyclovir, ticlopidine)Avoid; if necessary reduce or stop tizanidine if hypotension, bradycardia or excessive drowsiness occur.DailyMed (U.S. National Library of Medicine)
• Oral contraceptivesConcomitant use not recommended; reduce or discontinue if adverse reactions occur.DailyMed (U.S. National Library of Medicine)

• No adequate human data; animal studies showed developmental toxicity (embryofetal and offspring mortality, growth deficits) at doses below clinical exposure.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No human milk data; present in milk of lactating animals; weigh benefits of breastfeeding against maternal need and infant risk.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Tizanidine: Central alpha-2 adrenergic agonist; presumably reduces spasticity by increasing presynaptic inhibition of motor neurons (Dawa Prices pharmacology text; US label class).