سعر يونيترين Unitrin‏ 25مجم 30 كبسولة 2026

Acitretin 25 mg capsules, pack of 30.

• Adverse reactions largely resemble hypervitaminosis A: mucocutaneous (cheilitis, dryness, alopecia, peeling), musculoskeletal, hepatic, neuropsychiatric and CNS effects.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Pregnancy or possible pregnancy during treatment or within 3 years after; severe hepatic or renal impairment; chronic abnormally elevated blood lipids; concomitant methotrexate or tetracyclines; hypersensitivity to acitretin or other retinoids.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: can cause severe birth defects; females must avoid pregnancy for at least 3 years after stopping, and must not ingest ethanol during treatment and for 2 months after. Should be prescribed only by those knowledgeable in systemic retinoids.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Hepatotoxicity, lipid elevations, pseudotumor cerebri (especially with tetracyclines) and hyperostosis are reported.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• MethotrexateCombination contraindicated (increased risk of hepatitis).DailyMed (U.S. National Library of Medicine)
• TetracyclinesCombination contraindicated (both can increase intracranial pressure).DailyMed (U.S. National Library of Medicine)
• EthanolIn females, ethanol may convert acitretin to etretinate (long half-life); avoid during and for 2 months after therapy.DailyMed (U.S. National Library of Medicine)

• Contraindicated: severe birth defects reported; pregnancy must be avoided during therapy and for at least 3 years after discontinuation.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Nursing mothers should not receive acitretin prior to or during nursing; acitretin has been reported in human milk.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Acitretin: Retinoid acting on nuclear retinoid receptors (RAR/RXR) to normalize epidermal cell differentiation and proliferation; exact mechanism unknown.