سعر كازيت 10/40 مجم 7 أقراص مغلفة 2022

Cazet 10/40 mg film-coated tablets (ezetimibe 10 mg + simvastatin 40 mg), 7 count, Unipharma > 4A Pharma-Egypt.

• Adjunct to diet for primary hyperlipidemia / mixed hyperlipidemia to reduce elevated total-C, LDL-C, Apo B, triglycerides and non-HDL-C, and to increase HDL-C (US ezetimibe/simvastatin).Population: AdultsDailyMed (U.S. NLM)

• Active liver disease or unexplained persistent elevations of hepatic transaminases; concomitant strong CYP3A4 inhibitors, gemfibrozil, cyclosporine, danazol; hypersensitivity; pregnancy and lactation (US label for simvastatin-containing products).International label, equivalent formulation · DailyMed (U.S. NLM)

• Myopathy/rhabdomyolysis risk with simvastatin — dose limits with interacting drugs; monitor muscle symptoms. Hepatic enzyme monitoring recommended.International label, equivalent formulation · DailyMed (U.S. NLM)

• Strong CYP3A4 inhibitors / gemfibrozil / cyclosporine / danazolMajorContraindicated — increased myopathy risk.DailyMed (U.S. NLM)
• Amiodarone / amlodipine / ranolazine / verapamil / diltiazemModerateSimvastatin dose limits apply (see US label).DailyMed (U.S. NLM)

• Statins are contraindicated in pregnancy and lactation (US ezetimibe/simvastatin labelling).International label, equivalent formulation · DailyMed (U.S. NLM)

• Ezetimibe: Inhibits intestinal absorption of cholesterol and related phytosterols (US Vytorin label).
• Simvastatin: Inhibits HMG-CoA reductase, the rate-limiting enzyme of cholesterol synthesis (US Vytorin label).