سعر كونتروبيس-اتش 5/12.5مجم 20 قرص 2022

Contropace-h 5/12.5mg 20 f.c. tabs.: Bisoprolol fumarate 5 mg + hydrochlorothiazide 12.5 mg (Amriya).

• Management of hypertension (US bisoprolol fumarate/hydrochlorothiazide labeling). Confirm Egyptian leaflet for approved indications.Population: Adults with hypertensionDailyMed (NLM)

• Fatigue, dizziness, bradycardia, hypokalemia and other electrolyte changes may occur (combination beta-blocker/thiazide context).International label, equivalent formulation · DailyMed (NLM)

• Cardiogenic shock, overt cardiac failure, second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component or to other sulfonamide-derived drugs (US label).International label, equivalent formulation · DailyMed (NLM)

• Abrupt beta-blocker withdrawal may exacerbate angina or cause MI in coronary disease; caution in heart failure, bronchospastic disease, diabetes (mask hypoglycemia), peripheral vascular disease; thiazides may cause electrolyte imbalance and precipitate gout (US label context).International label, equivalent formulation · DailyMed (NLM)

• Other antihypertensives / calcium channel blockers / digoxinModerateAdditive bradycardia, AV block or hypotension risk; monitor.DailyMed (NLM)

• Beta-blockers and thiazides may cause fetal/neonatal adverse effects; use in pregnancy only if potential benefit justifies risk (US combination label context). Confirm Egyptian leaflet.International label, equivalent formulation · DailyMed (NLM)

• Bisoprolol fumarate: Highly beta-1-selective adrenoceptor blocker without intrinsic sympathomimetic or relevant membrane-stabilising activity; reduces heart rate, contractility and sympathetic drive.
• Hydrochlorothiazide: Promotes renal excretion of sodium and chloride, reducing intravascular volume.