سعر فنجيكان 150 مجم 2 كبسولة 2023

Fluconazole 150 mg capsules, 2 per pack, by Amoun (Egypt); listed as an antifungal.

• UK Diflucan: fungal infections including vaginal candidiasis (acute or recurrent) and candidal balanitis when local therapy is not appropriate, mucosal and invasive candidiasis, cryptococcosis, coccidioidomycosis, dermatomycoses and onychomycosis, and prophylaxis indications (e.g. reducing recurrent vaginal candidiasis). The 150 mg single-dose capsule is used for vaginal candidiasis and candidal balanitis.Population: Adults (vaginal candidiasis, candidal balanitis)electronic medicines compendium (eMC)

• Most frequent (1-10%): headache, abdominal pain, diarrhoea, nausea, vomiting, raised ALT, AST and alkaline phosphatase, and rash.International label, equivalent formulation · electronic medicines compendium (eMC)

• Hypersensitivity to fluconazole, related azoles or excipients; terfenadine with multiple fluconazole doses of 400 mg/day or more; QT-prolonging CYP3A4 substrates such as cisapride, astemizole, pimozide, quinidine and erythromycin.International label, equivalent formulation · electronic medicines compendium (eMC)

• Rare serious hepatotoxicity (including fatalities), usually reversible; QT prolongation and torsades de pointes (very rare); caution in renal dysfunction; possible adrenal insufficiency; serious skin reactions; moderate CYP2C9 and CYP3A4 inhibitor and strong CYP2C19 inhibitor; not for tinea capitis. Capsules contain lactose.International label, equivalent formulation · electronic medicines compendium (eMC)

• Observational studies suggest an increased risk of spontaneous abortion with first/second-trimester use; cumulative doses of 150 mg or less in the first trimester showed no overall increase in malformations. After a single dose, a 1-week washout is recommended before becoming pregnant.International label, equivalent formulation · electronic medicines compendium (eMC)
• Passes into breast milk at concentrations similar to plasma; breastfeeding may be maintained after a single 150 mg dose, but is not recommended after repeated or high-dose use.International label, equivalent formulation · electronic medicines compendium (eMC)

• Fluconazole: Inhibits fungal cytochrome P-450-mediated 14-alpha-lanosterol demethylation, an essential step in ergosterol biosynthesis (UK Diflucan SmPC).