سعر فانجيترانازول 100مجم 10 كبسولات 2022

Itraconazole 100 mg oral capsules, pack of 10; a triazole antifungal.

• Blastomycosis (pulmonary and extrapulmonary)Population: Adults (immunocompromised and non-immunocompromised)DailyMed (U.S. National Library of Medicine)
• Histoplasmosis, including chronic cavitary pulmonary disease and disseminated non-meningeal histoplasmosisPopulation: Adults (immunocompromised and non-immunocompromised)DailyMed (U.S. National Library of Medicine)
• Pulmonary and extrapulmonary aspergillosis in patients intolerant of or refractory to amphotericin BPopulation: Adults (immunocompromised and non-immunocompromised)DailyMed (U.S. National Library of Medicine)

• Boxed warning: do not use for onychomycosis in patients with ventricular dysfunction such as congestive heart failure or a history of CHF; discontinue if signs of CHF occur.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Boxed warning: coadministration with many CYP3A4 substrates is contraindicated, for example methadone, disopyramide, dofetilide, dronedarone, quinidine, ergot alkaloids, irinotecan, lurasidone, oral midazolam, pimozide, triazolam, felodipine, nisoldipine, ivabradine, ranolazine, eplerenone, cisapride, naloxegol, lomitapide, lovastatin, simvastatin, avanafil, ticagrelor, finerenone and voclosporin; raised levels can cause QT prolongation and torsades de pointes.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Rare cases of serious hepatotoxicity, including liver failure and death, some within the first week; stop treatment and test liver function if signs of liver disease develop.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Teratogenic in rats and mice at doses 1-4 times the maximum human dose; no studies in pregnant women. Use for systemic fungal infections in pregnancy only if the benefit outweighs the risk; do not use for onychomycosis in pregnant women or women contemplating pregnancy.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Itraconazole is excreted in human milk; weigh the expected benefit for the mother against the risk to the infant.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Itraconazole: Inhibits cytochrome P450-dependent synthesis of ergosterol, a vital component of fungal cell membranes.