سعر ميفاكور 5مجم 20 اقراص 2022

Bisoprolol fumarate 5 mg film-coated tablets (selective beta-1 blocker) by Sigma, Egypt.

• Management of hypertension, alone or in combination with other antihypertensive agentsPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Commonly reported in hypertension trials: headache, dizziness, fatigue, diarrhea, upper respiratory infection, rhinitis, arthralgia, insomnia and bradycardia.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Cardiogenic shock, overt cardiac failure, second- or third-degree AV block, and marked sinus bradycardia.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Do not stop abruptly: exacerbation of angina, myocardial infarction and ventricular arrhythmias have occurred after abrupt cessation of beta-blockers in coronary artery disease; taper over about one week.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Use with caution in compensated cardiac failure, bronchospastic disease (lowest effective dose), peripheral vascular disease, major surgery/anaesthesia, and diabetes (may mask tachycardia of hypoglycemia); may mask signs of hyperthyroidism.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Other beta-blockers; catecholamine-depleting drugs (reserpine, guanethidine)Should not be combined with other beta-blocking agents; with catecholamine-depleting drugs monitor closely for excessive reduction of sympathetic activity.DailyMed (U.S. National Library of Medicine)
• ClonidineIf co-administered and to be withdrawn, discontinue bisoprolol several days before clonidine.DailyMed (U.S. National Library of Medicine)
• Myocardial depressants or AV-conduction inhibitors (verapamil, diltiazem), antiarrhythmics (disopyramide), digitalisUse with caution; additive effects on myocardial function and AV conduction.DailyMed (U.S. National Library of Medicine)

• Small amounts (<2% of the dose) are found in rat milk; it is not known whether bisoprolol is excreted in human milk; exercise caution in nursing women.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

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