سعر اموتينولول 50 مجم 10 أقراص 2022

Atenolol 50 mg film-coated tablets, pack of 10 (1 strip); cardioselective beta-blocker.

• Hypertension, alone or with other antihypertensive agents (especially thiazide-type diuretics)Population: AdultsDailyMed (U.S. National Library of Medicine)
• Long-term management of angina pectoris due to coronary atherosclerosisPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Hemodynamically stable patients with definite or suspected acute myocardial infarction, to reduce cardiovascular mortalityPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Adverse reactions in controlled hypertension trials include bradycardia (3%), cold extremities, postural hypotension, dizziness, vertigo, light-headedness, tiredness, fatigue, lethargy, drowsiness, depression, diarrhea and nausea.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Sinus bradycardia, heart block greater than first degree, cardiogenic shock, overt cardiac failure, and hypersensitivity to atenolol or any of the drug product components.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Cessation of therapy: patients with coronary artery disease should be advised against abrupt discontinuation - severe exacerbation of angina, myocardial infarction and ventricular arrhythmias have been reported after abrupt discontinuation of beta-blockers; when discontinuation is planned, observe carefully and limit physical activity; it may be prudent not to stop abruptly even in patients treated only for hypertension.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Cardiac failure: beta-blockade may precipitate more severe failure; bronchospastic disease: patients generally should not receive beta-blockers (atenolol may be used with caution at the lowest possible dose).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Beta-blockers may prevent early warning signs of hypoglycemia (e.g., tachycardia) and increase the risk of severe or prolonged hypoglycemia; beta-blockade may mask signs of hyperthyroidism (abrupt withdrawal may precipitate thyroid storm); do not give in untreated pheochromocytoma; chronic therapy should not routinely be withdrawn before major surgery, but anesthesia risks may be augmented.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Catecholamine-depleting drugs (e.g., reserpine)May have an additive effect; observe closely for hypotension and/or marked bradycardia.DailyMed (U.S. National Library of Medicine)
• Calcium channel blockers (e.g., verapamil, diltiazem)Bradycardia and heart block can occur and left ventricular end-diastolic pressure can rise.DailyMed (U.S. National Library of Medicine)
• Disopyramide and amiodaroneAdditive negative effects on conduction and contractility (disopyramide: significant negative inotropic and chronotropic effects).DailyMed (U.S. National Library of Medicine)

• Atenolol can cause fetal harm: it crosses the placenta, and administration starting in the second trimester has been associated with infants small for gestational age; first-trimester risk cannot be excluded. Neonates exposed at parturition or through breast milk may be at risk of hypoglycemia and bradycardia.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Atenolol is excreted in human breast milk at a ratio of 1.5 to 6.8 compared with plasma; clinically significant bradycardia has been reported in breastfed infants. Caution should be exercised.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Atenolol: Beta1-selective beta-adrenergic receptor blocker without membrane-stabilizing or intrinsic sympathomimetic activity; selectivity is not absolute and higher doses also inhibit beta2 receptors (US label).