سعر لو بريس 100مجم 20 قرص 2022

Metoprolol tartrate 100 mg tablets (Hi-Pharm, Egypt); cardioselective beta-blocker for hypertension and angina.

• Hypertension, to lower blood pressurePopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Angina pectorisPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Myocardial infarction, to reduce cardiovascular mortality in hemodynamically stable patients (with intravenous metoprolol initially)Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common: tiredness, dizziness, depression, shortness of breath, bradycardia, hypotension, diarrhea, pruritus and rash.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Severe bradycardia, second- or third-degree heart block.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Cardiogenic shock or decompensated heart failure.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Sick sinus syndrome unless a permanent pacemaker is in place.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Abrupt cessation may exacerbate myocardial ischemia; taper over 1-2 weeks.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Worsening cardiac failure may occur.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Bronchospastic disease: generally avoid beta-blockers.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• CYP2D6 inhibitors (e.g. quinidine, fluoxetine, paroxetine, propafenone)May increase metoprolol concentrations.DailyMed (U.S. National Library of Medicine)
• Catecholamine-depleting drugs (e.g. reserpine, MAO inhibitors)Additive effects; observe for hypotension or marked bradycardia.DailyMed (U.S. National Library of Medicine)
• Digitalis glycosides, clonidine, diltiazem, verapamilIncreased risk of bradycardia; with clonidine, rebound hypertension on withdrawal.DailyMed (U.S. National Library of Medicine)

• Published observational studies have not shown an association of adverse developmental outcomes with maternal metoprolol use; untreated hypertension and MI in pregnancy carry risks.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Metoprolol is present in human milk (estimated infant dose 0.05 to <1 mg/day, 0.5-2% of maternal weight-adjusted dose); no adverse effects on breastfed infants identified.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Metoprolol tartrate: Beta1-selective (cardioselective) adrenergic blocker without intrinsic sympathomimetic activity; selectivity is not absolute at higher concentrations.