سعر نيبفول 5مجم 10 اقراص 2022

Nebivolol (as hydrochloride) 5 mg tablets, pack of 10, a beta-1 selective beta blocker for hypertension, by Advocure (Egypt).

• Treatment of hypertension, to lower blood pressure, alone or with other antihypertensivesPopulation: AdultsDailyMed (US National Library of Medicine)

• Most common: headache and fatigue.International label, equivalent formulation · DailyMed (US National Library of Medicine)

• Severe bradycardia; heart block greater than first degree; cardiogenic shock; decompensated cardiac failure; sick sinus syndrome without a permanent pacemaker.International label, equivalent formulation · DailyMed (US National Library of Medicine)
• Severe hepatic impairment (Child-Pugh >B); hypersensitivity to any component.International label, equivalent formulation · DailyMed (US National Library of Medicine)

• Do not stop abruptly in coronary artery disease (risk of severe angina exacerbation, MI, ventricular arrhythmias); taper over 1-2 weeks.International label, equivalent formulation · DailyMed (US National Library of Medicine)
• May mask symptoms of hypoglycaemia (tachycardia) and alter glucose levels in diabetes; monitor.International label, equivalent formulation · DailyMed (US National Library of Medicine)

• CYP2D6 inhibitors (quinidine, propafenone, fluoxetine, paroxetine)May increase nebivolol levels; use caution.DailyMed (US National Library of Medicine)
• Reserpine, clonidine, other beta blockersExcessive reduction of sympathetic activity; do not combine with other beta blockers.DailyMed (US National Library of Medicine)
• Digitalis glycosidesAdditive slowing of AV conduction and heart rate; bradycardia risk.DailyMed (US National Library of Medicine)

• US label: data insufficient to determine drug-associated developmental risk; poorly controlled hypertension carries maternal/fetal risk; third-trimester beta blocker use may cause neonatal hypotension, bradycardia, hypoglycaemia and respiratory depression.International label, equivalent formulation · DailyMed (US National Library of Medicine)
• Not recommended during breastfeeding (potential for serious adverse reactions such as bradycardia in the infant); no human milk data.International label, equivalent formulation · DailyMed (US National Library of Medicine)

• Nebivolol hydrochloride: Beta-adrenergic receptor blocker; antihypertensive mechanism not definitively established (reduced heart rate and contractility, reduced sympathetic outflow, renin suppression, vasodilation) per the US BYSTOLIC label.