سعر اوفلوجايد 400مجم 10 اقراص 2022

Ofloguide 400mg 10 f.c.tab: Ofloxacin 400 mg film-coated tablet (10 film-coated tablets) marketed in Egypt by Bioriginal International Group Pharma > Genesis Pharmaceuticals.

• Mild to moderate bacterial infections in adults caused by susceptible bacteria (e.g., acute bacterial exacerbation of chronic bronchitis, community-acquired pneumonia, uncomplicated skin infections, urethral and cervical gonorrhoea, urinary tract infections, prostatitis), per label restrictionsPopulation: Adults (18 years and older)DailyMed (U.S. National Library of Medicine)

• Drug-related events in multiple-dose trials included nausea (3%), insomnia (3%), headache, dizziness, diarrhoea, vomiting, rash, pruritus, external genital pruritus, vaginitis and dysgeusia (about 1% each).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• History of hypersensitivity to ofloxacin or any member of the quinolone group.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: fluoroquinolones are associated with disabling and potentially irreversible serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy and central nervous system effects, and may exacerbate muscle weakness in myasthenia gravis.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Antacids (Ca/Mg/Al), sucralfate, iron, zinc, didanosineChelation markedly reduces quinolone absorption; separate by at least 2 hours before or after ofloxacin.DailyMed (U.S. National Library of Medicine)

• No teratogenic effects in rats and rabbits at high oral doses; no adequate and well-controlled studies in pregnant women. Use only if the potential benefit justifies the potential risk to the fetus.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• A single 200 mg oral dose produced milk concentrations similar to plasma; decide whether to discontinue nursing or the drug.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Ofloxacin: Inhibits bacterial DNA gyrase and topoisomerase IV, blocking bacterial DNA replication.