سعر اولفين دي ايه 75مجم 10 كبسولات 2022

Olfen 75 mg D.A. (dual-action) depocapsules: oral NSAID capsules combining diclofenac potassium and diclofenac sodium (75 mg diclofenac in total), for pain and inflammation; 10 capsules per pack.

• Common: headache, dizziness, vertigo, nausea, vomiting, diarrhoea, dyspepsia, abdominal pain, flatulence, anorexia, raised transaminases, rash.General active-ingredient information · electronic medicines compendium (emc)

• Active gastric or intestinal ulcer, bleeding or perforation; history of NSAID-related GI bleeding/perforation; active or recurrent peptic ulcer/haemorrhage.General active-ingredient information · electronic medicines compendium (emc)
• Established congestive heart failure (NYHA II-IV), ischaemic heart disease, peripheral arterial disease and/or cerebrovascular disease; hepatic failure; renal failure.General active-ingredient information · electronic medicines compendium (emc)
• Last trimester of pregnancy; hypersensitivity, including asthma, angioedema, urticaria or rhinitis precipitated by aspirin or other NSAIDs.General active-ingredient information · electronic medicines compendium (emc)

• Use the lowest effective dose for the shortest duration; increased risk of arterial thrombotic events (myocardial infarction, stroke), particularly at 150 mg daily and with long-term use.General active-ingredient information · electronic medicines compendium (emc)
• Gastrointestinal bleeding, ulceration or perforation (sometimes fatal) may occur at any time, more seriously in the elderly; consider gastroprotection in at-risk patients.General active-ingredient information · electronic medicines compendium (emc)
• Caution in hepatic, renal or cardiac impairment and hypertension (fluid retention, oedema); serious skin reactions (SJS/TEN) can occur, stop at first rash.General active-ingredient information · electronic medicines compendium (emc)

• Lithium, digoxinMay raise plasma lithium and digoxin levels; monitor serum levels.electronic medicines compendium (emc)
• Diuretics, ACE inhibitors, beta-blockersReduced antihypertensive effect and increased nephrotoxicity risk; monitor blood pressure and renal function.electronic medicines compendium (emc)
• Anticoagulants, antiplatelets, SSRIs, corticosteroids, other NSAIDsIncreased risk of bleeding or gastrointestinal ulceration.electronic medicines compendium (emc)
• Methotrexate, ciclosporin, tacrolimusIncreased methotrexate toxicity and nephrotoxicity.electronic medicines compendium (emc)

• Should not be given in the first and second trimester unless clearly necessary; from week 20 it may cause oligohydramnios and ductus arteriosus constriction.General active-ingredient information · electronic medicines compendium (emc)
• Passes into breast milk in small amounts; should not be administered during breast-feeding.General active-ingredient information · electronic medicines compendium (emc)

• Monitor renal and hepatic function and blood counts during prolonged treatment, and blood pressure with antihypertensives.General active-ingredient information · electronic medicines compendium (emc)

• Diclofenac potassium: Inhibits prostaglandin synthetase (cyclo-oxygenase), producing analgesic and anti-inflammatory effects.
• Diclofenac sodium: Inhibits prostaglandin synthetase (cyclo-oxygenase), producing analgesic and anti-inflammatory effects.