سعر ريبازول 400مجم 30 كبسول 2022
Ribazole 400mg 30 caps- المادة الفعالة: Ribavirin
- Adwia
- عن طريق الفم
الفئة: مضاد فيروسات
معلومات الدواء
التفاصيل الكاملةدواعي الاستعمالUses
- In combination with interferon alfa-2b (pegylated or non-pegylated) for chronic hepatitis C in patients 3 years and older with compensated liver disease; ribavirin monotherapy is not effective for CHC.DailyMed (U.S. National Library of Medicine)
- In combination with interferon alfa-2b (pegylated or non-pegylated) for chronic hepatitis C in patients 3 years and older with compensated liver disease; ribavirin monotherapy is not effective for CHC.DailyMed (U.S. National Library of Medicine)
الآثار الجانبيةSide effects
- Hemolytic anemia occurred in more than 10% of adults receiving ribavirin with peginterferon/interferon alfa-2b.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
- Most common adverse reactions (40% or more) in adults on combination therapy: injection site reaction, fatigue/asthenia, headache, rigors, fever, nausea, myalgia and anxiety/emotional lability/irritability.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
- Hemolytic anemia occurred in more than 10% of adults receiving ribavirin with peginterferon/interferon alfa-2b.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
- Most common adverse reactions (40% or more) in adults on combination therapy: injection site reaction, fatigue/asthenia, headache, rigors, fever, nausea, myalgia and anxiety/emotional lability/irritability.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
موانع الاستعمالContraindications
- Pregnancy; ribavirin may cause fetal harm and is contraindicated in women who are pregnant or planning pregnancy.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
- Men whose female partners are pregnant.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
- Known hypersensitivity reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis or erythema multiforme to ribavirin or any component.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
- Pregnancy; ribavirin may cause fetal harm and is contraindicated in women who are pregnant or planning pregnancy.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
- Men whose female partners are pregnant.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
- Known hypersensitivity reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis or erythema multiforme to ribavirin or any component.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطاتWarnings & precautions
- Boxed warning - embryo-fetal toxicity: significant teratogenic/embryocidal effects in all animal species; avoid pregnancy and use effective contraception during therapy and for 9 months after treatment in female patients and for 6 months in female partners of male patients.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
- Boxed warning - hemolytic anemia, which may worsen cardiac disease and has led to fatal and nonfatal myocardial infarction; patients with significant or unstable cardiac disease should not be treated.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
- Ribavirin monotherapy is not effective for chronic hepatitis C and should not be used alone for this indication.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
- Boxed warning - embryo-fetal toxicity: significant teratogenic/embryocidal effects in all animal species; avoid pregnancy and use effective contraception during therapy and for 9 months after treatment in female patients and for 6 months in female partners of male patients.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
- Boxed warning - hemolytic anemia, which may worsen cardiac disease and has led to fatal and nonfatal myocardial infarction; patients with significant or unstable cardiac disease should not be treated.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
- Ribavirin monotherapy is not effective for chronic hepatitis C and should not be used alone for this indication.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
التداخلات الدوائيةDrug interactions
- DidanosineIncreased exposure to didanosine active metabolite; fatal hepatic failure, peripheral neuropathy, pancreatitis and lactic acidosis reported; coadministration contraindicated.DailyMed (U.S. National Library of Medicine)
- Nucleoside reverse transcriptase inhibitorsHepatic decompensation (some fatal) in cirrhotic HIV/HCV co-infected patients; monitor closely for toxicities including anemia.DailyMed (U.S. National Library of Medicine)
- AzathioprineSevere pancytopenia reported; ribavirin inhibits IMPDH and may increase azathioprine-related myelotoxicity.DailyMed (U.S. National Library of Medicine)
- DidanosineIncreased exposure to didanosine active metabolite; fatal hepatic failure, peripheral neuropathy, pancreatitis and lactic acidosis reported; coadministration contraindicated.DailyMed (U.S. National Library of Medicine)
- Nucleoside reverse transcriptase inhibitorsHepatic decompensation (some fatal) in cirrhotic HIV/HCV co-infected patients; monitor closely for toxicities including anemia.DailyMed (U.S. National Library of Medicine)
- AzathioprineSevere pancytopenia reported; ribavirin inhibits IMPDH and may increase azathioprine-related myelotoxicity.DailyMed (U.S. National Library of Medicine)
الحمل والرضاعةPregnancy & breastfeeding
- Contraindicated in pregnant women and in men whose female partners are pregnant; animal data show teratogenic and/or embryocidal effects, and Ribavirin Pregnancy Registry data showed higher birth-defect rates than background.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
- No data on presence of ribavirin in human milk or effects on the breastfed infant; weigh benefits of breastfeeding against maternal need and potential infant risk.معلومة عامة عن المادة الفعالة · DailyMed (U.S. National Library of Medicine)
- Contraindicated in pregnant women and in men whose female partners are pregnant; animal data show teratogenic and/or embryocidal effects, and Ribavirin Pregnancy Registry data showed higher birth-defect rates than background.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
- No data on presence of ribavirin in human milk or effects on the breastfed infant; weigh benefits of breastfeeding against maternal need and potential infant risk.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
كيف يعمل الدواءHow it works
- Nucleoside (guanosine) analogue antiviral; per the US label the mechanism by which ribavirin contributes to antiviral efficacy against HCV is not fully understood.
- Ribavirin: Nucleoside (guanosine) analogue antiviral; per the US label the mechanism by which ribavirin contributes to antiviral efficacy against HCV is not fully understood.
المثائل (5)
كل المثائل والبدائلنفس المادة الفعالة والتركيز. اسأل الصيدلي قبل الاستبدال.
| الدواء | السعر | الفرق عن الأصلي |
|---|---|---|
| ريبافارين 400مجم 12 كبسولRibavarin 400 mg 12 capsulesMemphis · 400 mgالأرخص | السعر28.8ج.م2.4ج.م للوحدة | الفرق عن الأصليأرخص 37.2ج.م (56.4%) |
| ريبافيرين 400مجم 12 كبسولRibavirin 400 mg 12 capsulesMina Pharm · 400 mg | السعر38ج.م3.17ج.م للوحدة | الفرق عن الأصليأرخص 28ج.م (42.4%) |
| بانفيرين 400 مجم 10 كبسولاتPanvirin 400 mg hard gelatin capsulesAlfacure Pharmaceuticals · كبسولات جيلاتينية صلبة · 400 mg | السعر48ج.م4.8ج.م للوحدة | الفرق عن الأصليأرخص 18ج.م (27.3%) |
| ريبا 400مجم 10 كبسولRiba 400 mg 10 capsulesGlobal Napi Pharmaceuticals · 400 mg | السعر48ج.م4.8ج.م للوحدة | الفرق عن الأصليأرخص 18ج.م (27.3%) |
| هيباتوفيرين 400 مجم 30 كبسولةHepatovirin 400 mg 30 capEgypharma-Egypt · كبسولة · 400 mg | السعر60ج.م2ج.م للوحدة | الفرق عن الأصليأرخص 6ج.م (9.1%) |
أدوية ذات صلة
نفس المادة الفعالة بتركيز آخر
منتجات أخرى من Adwia
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- DailyMed (U.S. National Library of Medicine)
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