سعر ريبوفينال 200مجم 8 كبسول 2022
Ribovinal 200 mg 8 caps- المادة الفعالة: Ribavirin
- Mash Premiere
- عن طريق الفم
الفئة: مضاد فيروسات
معلومات الدواء
التفاصيل الكاملةدواعي الاستعمالUses
- In combination with interferon alfa-2b (pegylated or non-pegylated) for chronic hepatitis C in patients 3 years and older with compensated liver disease; ribavirin monotherapy is not effective for CHC.DailyMed (U.S. National Library of Medicine)
- In combination with interferon alfa-2b (pegylated or non-pegylated) for chronic hepatitis C in patients 3 years and older with compensated liver disease; ribavirin monotherapy is not effective for CHC.DailyMed (U.S. National Library of Medicine)
الآثار الجانبيةSide effects
- Hemolytic anemia occurred in more than 10% of adults receiving ribavirin with peginterferon/interferon alfa-2b.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Most common adverse reactions (40% or more) in adults on combination therapy: injection site reaction, fatigue/asthenia, headache, rigors, fever, nausea, myalgia and anxiety/emotional lability/irritability.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Hemolytic anemia occurred in more than 10% of adults receiving ribavirin with peginterferon/interferon alfa-2b.International label, same formulation · DailyMed (U.S. National Library of Medicine)
- Most common adverse reactions (40% or more) in adults on combination therapy: injection site reaction, fatigue/asthenia, headache, rigors, fever, nausea, myalgia and anxiety/emotional lability/irritability.International label, same formulation · DailyMed (U.S. National Library of Medicine)
موانع الاستعمالContraindications
- Pregnancy; ribavirin may cause fetal harm and is contraindicated in women who are pregnant or planning pregnancy.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Men whose female partners are pregnant.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Known hypersensitivity reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis or erythema multiforme to ribavirin or any component.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Pregnancy; ribavirin may cause fetal harm and is contraindicated in women who are pregnant or planning pregnancy.International label, same formulation · DailyMed (U.S. National Library of Medicine)
- Men whose female partners are pregnant.International label, same formulation · DailyMed (U.S. National Library of Medicine)
- Known hypersensitivity reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis or erythema multiforme to ribavirin or any component.International label, same formulation · DailyMed (U.S. National Library of Medicine)
تحذيرات واحتياطاتWarnings & precautions
- Boxed warning - embryo-fetal toxicity: significant teratogenic/embryocidal effects in all animal species; avoid pregnancy and use effective contraception during therapy and for 9 months after treatment in female patients and for 6 months in female partners of male patients.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Boxed warning - hemolytic anemia, which may worsen cardiac disease and has led to fatal and nonfatal myocardial infarction; patients with significant or unstable cardiac disease should not be treated.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Ribavirin monotherapy is not effective for chronic hepatitis C and should not be used alone for this indication.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Boxed warning - embryo-fetal toxicity: significant teratogenic/embryocidal effects in all animal species; avoid pregnancy and use effective contraception during therapy and for 9 months after treatment in female patients and for 6 months in female partners of male patients.International label, same formulation · DailyMed (U.S. National Library of Medicine)
- Boxed warning - hemolytic anemia, which may worsen cardiac disease and has led to fatal and nonfatal myocardial infarction; patients with significant or unstable cardiac disease should not be treated.International label, same formulation · DailyMed (U.S. National Library of Medicine)
- Ribavirin monotherapy is not effective for chronic hepatitis C and should not be used alone for this indication.International label, same formulation · DailyMed (U.S. National Library of Medicine)
التداخلات الدوائيةDrug interactions
- DidanosineIncreased exposure to didanosine active metabolite; fatal hepatic failure, peripheral neuropathy, pancreatitis and lactic acidosis reported; coadministration contraindicated.DailyMed (U.S. National Library of Medicine)
- Nucleoside reverse transcriptase inhibitorsHepatic decompensation (some fatal) in cirrhotic HIV/HCV co-infected patients; monitor closely for toxicities including anemia.DailyMed (U.S. National Library of Medicine)
- AzathioprineSevere pancytopenia reported; ribavirin inhibits IMPDH and may increase azathioprine-related myelotoxicity.DailyMed (U.S. National Library of Medicine)
- DidanosineIncreased exposure to didanosine active metabolite; fatal hepatic failure, peripheral neuropathy, pancreatitis and lactic acidosis reported; coadministration contraindicated.DailyMed (U.S. National Library of Medicine)
- Nucleoside reverse transcriptase inhibitorsHepatic decompensation (some fatal) in cirrhotic HIV/HCV co-infected patients; monitor closely for toxicities including anemia.DailyMed (U.S. National Library of Medicine)
- AzathioprineSevere pancytopenia reported; ribavirin inhibits IMPDH and may increase azathioprine-related myelotoxicity.DailyMed (U.S. National Library of Medicine)
الحمل والرضاعةPregnancy & breastfeeding
- Contraindicated in pregnant women and in men whose female partners are pregnant; animal data show teratogenic and/or embryocidal effects, and Ribavirin Pregnancy Registry data showed higher birth-defect rates than background.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- No data on presence of ribavirin in human milk or effects on the breastfed infant; weigh benefits of breastfeeding against maternal need and potential infant risk.نشرة دولية لنفس التركيبة · DailyMed (U.S. National Library of Medicine)
- Contraindicated in pregnant women and in men whose female partners are pregnant; animal data show teratogenic and/or embryocidal effects, and Ribavirin Pregnancy Registry data showed higher birth-defect rates than background.International label, same formulation · DailyMed (U.S. National Library of Medicine)
- No data on presence of ribavirin in human milk or effects on the breastfed infant; weigh benefits of breastfeeding against maternal need and potential infant risk.International label, same formulation · DailyMed (U.S. National Library of Medicine)
كيف يعمل الدواءHow it works
- Nucleoside (guanosine) analogue antiviral; per the US label the mechanism by which ribavirin contributes to antiviral efficacy against HCV is not fully understood.
- Ribavirin: Nucleoside (guanosine) analogue antiviral; per the US label the mechanism by which ribavirin contributes to antiviral efficacy against HCV is not fully understood.
المثائل (7)
كل المثائل والبدائلنفس المادة الفعالة والتركيز. اسأل الصيدلي قبل الاستبدال.
| الدواء | السعر | الفرق عن الأصلي |
|---|---|---|
| ريبافيرين 200مجم 12 كبسولةRibavirin 200 mg 12 capsulesMina Pharm · 200 mgالأرخص | السعر22ج.م1.83ج.م للوحدة | الفرق عن الأصليأغلى 10ج.م (83.3%) |
| ريبافارين 200مجم 12 كبسولةRibavarin 200 mg 12 capsulesMemphis · 200 mg | السعر24ج.م2ج.م للوحدة | الفرق عن الأصليأغلى 12ج.م (100%) |
| ريبا 200مجم 10 كبسولRiba 200 mg 10 capsulesGlobal Napi Pharmaceuticals · 200 mg | السعر30ج.م3ج.م للوحدة | الفرق عن الأصليأغلى 18ج.م (150%) |
| بانفيرين 200 مجم 10 كبسولPanvirin 200 mg capsulesAlfacure Pharmaceuticals · كبسولات · 200 mg | السعر32ج.م3.2ج.م للوحدة | الفرق عن الأصليأغلى 20ج.م (166.7%) |
| ريبافيرين 200مجم 10 كبسولRibavirin 200 mg 10 capsulesT3A Pharma · 200 mg | السعر50ج.م5ج.م للوحدة | الفرق عن الأصليأغلى 38ج.م (316.7%) |
أدوية ذات صلة
نفس المادة الفعالة بتركيز آخر
منتجات أخرى من Mash Premiere
المصادر
- السعر: قوائم أسعار الأدوية المنشورة في مصر.
- DailyMed (U.S. National Library of Medicine)
تعليقات
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