سعر ستاتومين 100مجم 30 قرص 2024

Statomain 100 mg scored film-coated tablets, pack of 30 (Biomed, Egypt): fluvoxamine maleate, a selective serotonin reuptake inhibitor (SSRI).

• Treatment of obsessions and compulsions in patients with obsessive compulsive disorder (OCD).Population: Adults and children/adolescents 8 to 17 yearsDailyMed (U.S. National Library of Medicine)

• Most common (>=5% and at least twice placebo): nausea, somnolence, insomnia, asthenia, nervousness, dyspepsia, abnormal ejaculation, sweating, anorexia, tremor, vomiting.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Co-administration with tizanidine, thioridazine, alosetron or pimozide.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Use with MAOIs intended to treat psychiatric disorders, or within 14 days of stopping either drug; starting in patients treated with linezolid or intravenous methylene blue.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: increased risk of suicidal thinking and behaviour in children, adolescents and young adults taking antidepressants; monitor for clinical worsening and suicidality.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Serotonin syndrome, especially with other serotonergic agents; discontinue if it occurs.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Screen for bipolar disorder (risk of mania/hypomania); angle-closure glaucoma in untreated narrow angles; seizures (avoid in unstable epilepsy); hyponatraemia (elderly at greater risk); increased bleeding risk with NSAIDs, aspirin or anticoagulants; sexual dysfunction.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• CYP1A2/CYP2C9/CYP3A4/CYP2C19 substrates (fluvoxamine inhibits these enzymes)Fluvoxamine can raise levels of drugs metabolised by these enzymes; caution with narrow-therapeutic-index drugs.DailyMed (U.S. National Library of Medicine)
• TheophyllineClearance decreased; reduce theophylline dose by one-third and monitor.DailyMed (U.S. National Library of Medicine)
• WarfarinPlasma concentrations increased and prothrombin time prolonged; monitor and adjust the warfarin dose.DailyMed (U.S. National Library of Medicine)

• Decades of observational data have not identified a clear drug-associated risk of major birth defects or miscarriage; SSRI exposure in the month before delivery is associated with a less than 2-fold increased risk of postpartum haemorrhage; consider the risks of untreated depression.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Present in human milk; most cases show no adverse effects, but diarrhoea, vomiting, decreased sleep and agitation have been reported; monitor breastfed infants.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Fluvoxamine maleate: Selective serotonin reuptake inhibitor; its action in OCD is presumed to be linked to inhibition of serotonin reuptake in brain neurons (US label).