سعر تيرابيتات Terabitat‏ 100 مجم 4 كبسولات. 2026

Itraconazole 100 mg hard capsules, pack of 4 (Mash Premiere, Egypt); systemic triazole antifungal.

• In onychomycosis trials: elevated liver enzymes, gastrointestinal disorders, rash, hypertension, orthostatic hypotension, headache, malaise, myalgia, vasculitis and vertigo led to discontinuation in some patients; hypertriglyceridemia and rash/pruritus in fingernail trials.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Do not use for onychomycosis in patients with evidence of ventricular dysfunction such as congestive heart failure or a history of CHF.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Coadministration with certain CYP3A4 substrates is contraindicated (e.g. methadone, disopyramide, dofetilide, dronedarone, quinidine, ergot alkaloids, irinotecan, lurasidone, oral midazolam, pimozide, triazolam, felodipine, nisoldipine, ivabradine, ranolazine, eplerenone, cisapride, lovastatin, simvastatin, ticagrelor and others listed).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: congestive heart failure, cardiac effects and serious drug interactions (increased plasma levels of CYP3A4 substrates that can cause QT prolongation/ventricular tachyarrhythmias).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Rare serious hepatotoxicity including liver failure and death, some within the first week; consider liver function monitoring in all patients and stop if liver dysfunction develops.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• CYP3A4 substratesItraconazole is a strong CYP3A4 inhibitor; many CYP3A4 substrates are contraindicated or need dose adjustment/monitoring.DailyMed (U.S. National Library of Medicine)

• Itraconazole is excreted in human milk; weigh expected benefit to the mother against the risk to the infant.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Itraconazole: Inhibits fungal cytochrome P450-dependent conversion of lanosterol, blocking ergosterol synthesis (directory pharmacology note; consistent with US label class).