سعر Sigmacyn 750mg vial i.m. i.v. 2026

Sigmacyn 750 mg vial for IM/IV injection (ampicillin + sulbactam) by Sigma (Egypt), an aminopenicillin/beta-lactamase-inhibitor antibiotic.

• Skin and skin-structure, intra-abdominal and gynaecological infections caused by susceptible beta-lactamase-producing strains of the organisms listed in the label.Population: Adults (paediatric use: see US label precautions)DailyMed (U.S. National Library of Medicine)

• Local: pain at IM injection site (16%), pain at IV site (3%), thrombophlebitis (3%), phlebitis (1.2%); systemic: diarrhoea (3%) and rash (<2%) most frequent; <1%: itching, nausea, vomiting, candidiasis, fatigue, headache and others.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• History of serious hypersensitivity reactions (e.g. anaphylaxis, Stevens-Johnson syndrome) to ampicillin, sulbactam or other beta-lactams (penicillins, cephalosporins).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Previous history of cholestatic jaundice/hepatic dysfunction associated with ampicillin-sulbactam.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Serious, occasionally fatal hypersensitivity (anaphylactic) reactions; enquire about prior penicillin, cephalosporin and other allergen hypersensitivity before therapy.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Clostridioides difficile-associated diarrhoea, from mild diarrhoea to fatal colitis, has been reported.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• ProbenecidDecreases renal tubular secretion of ampicillin and sulbactam, giving increased and prolonged blood levels.DailyMed (U.S. National Library of Medicine)
• AllopurinolConcurrent allopurinol and ampicillin substantially increase the incidence of rash.DailyMed (U.S. National Library of Medicine)

• No harm to the fetus in mice, rats and rabbits at up to 10 times the human dose; no adequate studies in pregnant women; use in pregnancy only if clearly needed.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Low concentrations of ampicillin and sulbactam are excreted in milk; use with caution in nursing women.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)