سعر ميجاكلافوكس 1.2جم فيال وريد 2022

Amoxicillin + clavulanic acid 1.2 g powder in a vial for intravenous injection or infusion; CID, Egypt.

• Severe infections of the ear, nose and throat (e.g. mastoiditis, peritonsillar infections, epiglottitis, sinusitis with severe systemic signs).Population: Adults and childrenemc (medicines.org.uk)
• Acute exacerbations of chronic bronchitis; community-acquired pneumonia.Population: Adults and childrenemc (medicines.org.uk)
• Cystitis and pyelonephritis.Population: Adults and childrenemc (medicines.org.uk)

• Most commonly reported adverse reactions: diarrhoea, nausea and vomiting.International label, equivalent formulation · emc (medicines.org.uk)

• Hypersensitivity to the active substances or to any penicillin.International label, equivalent formulation · emc (medicines.org.uk)
• History of a severe immediate hypersensitivity reaction (e.g. anaphylaxis) to another beta-lactam agent (cephalosporin, carbapenem or monobactam).International label, equivalent formulation · emc (medicines.org.uk)
• History of jaundice or hepatic impairment due to amoxicillin/clavulanic acid.International label, equivalent formulation · emc (medicines.org.uk)

• Before starting, enquire carefully about previous hypersensitivity to penicillins, cephalosporins or other beta-lactams; serious and occasionally fatal hypersensitivity reactions (including severe cutaneous reactions and Kounis syndrome) have occurred - stop treatment if an allergic reaction occurs. Drug-induced enterocolitis syndrome has been reported mainly in children.International label, equivalent formulation · emc (medicines.org.uk)

• Oral anticoagulants (warfarin, acenocoumarol)Cases of increased INR have been reported; monitor prothrombin time/INR when amoxicillin is added or withdrawn and adjust anticoagulant dose if needed.emc (medicines.org.uk)
• MethotrexatePenicillins may reduce methotrexate excretion, potentially increasing toxicity.emc (medicines.org.uk)
• ProbenecidConcomitant use is not recommended; probenecid increases and prolongs amoxicillin (not clavulanic acid) blood levels.emc (medicines.org.uk)

• Limited human data do not indicate an increased risk of congenital malformations; in women with preterm premature rupture of membranes, prophylactic use may be associated with an increased risk of necrotising enterocolitis in neonates. Avoid in pregnancy unless considered essential.International label, equivalent formulation · emc (medicines.org.uk)
• Both substances pass into breast milk; diarrhoea and mucosal fungal infection are possible in the infant, so breastfeeding might have to be discontinued; use only after benefit/risk assessment.International label, equivalent formulation · emc (medicines.org.uk)

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