سعر لاسيداك 2 مجم 14 قرص 2022

Lacidipine 2 mg film-coated tablets, pack of 14 (2 strips), by Delta Pharma (Egypt); long-acting vascular-selective dihydropyridine calcium channel blocker for hypertension.

• Treatment of hypertension, alone or with other antihypertensives (beta-blockers, diuretics, ACE inhibitors).Population: Adultselectronic medicines compendium (emc), UK

• Common: dizziness, headache, palpitations, tachycardia, flushing, oedema, abdominal discomfort, nausea, rash, erythema, pruritus, polyuria, asthenia, increased blood alkaline phosphatase; uncommon: syncope, angina aggravation, hypotension, gingival hyperplasia; rare: angioedema, urticaria, muscle cramps; very rare: depression, tremor. Vasodilatory effects are usually transient.International label, same formulation · electronic medicines compendium (emc), UK

• Hypersensitivity to lacidipine or excipients; aortic stenosis; during or within one month of myocardial infarction; discontinue in cardiogenic shock and unstable angina; rare hereditary conditions incompatible with an excipient (lactose).International label, same formulation · electronic medicines compendium (emc), UK

• Use with caution in pre-existing SA or AV node abnormalities, congenital or acquired QT prolongation or with QT-prolonging drugs (class I/III antiarrhythmics, tricyclics, some antipsychotics, erythromycin, some antihistamines), poor cardiac reserve and impaired liver function; use with great care after a previous allergic reaction to another dihydropyridine.International label, same formulation · electronic medicines compendium (emc), UK
• Angina may be aggravated, especially at the start of treatment in symptomatic ischaemic heart disease; discontinue under supervision if unstable angina develops. Efficacy in malignant hypertension and secondary prevention of MI not established. May cause dizziness affecting driving.International label, same formulation · electronic medicines compendium (emc), UK

• Other antihypertensives (diuretics, beta-blockers, ACE inhibitors)Additive hypotensive effect possible; no specific interaction problems found with common antihypertensives, digoxin, tolbutamide or warfarin.electronic medicines compendium (emc), UK
• CYP3A4 inhibitors and inducers (e.g. itraconazole, rifampicin)May alter lacidipine metabolism and elimination.electronic medicines compendium (emc), UK
• CimetidineMay increase lacidipine plasma levels.electronic medicines compendium (emc), UK

• No data on safety in human pregnancy; animal data show no teratogenic effect but maternal toxicity at very high doses; use only when the potential benefit to the mother outweighs possible adverse effects in the fetus or neonate.International label, same formulation · electronic medicines compendium (emc), UK
• Animal studies suggest lacidipine or its metabolites are likely excreted into breast milk; use during breastfeeding only when the potential benefit outweighs the risk.International label, same formulation · electronic medicines compendium (emc), UK

• Lacidipine: Specific, potent calcium antagonist with predominant selectivity for calcium channels in vascular smooth muscle; dilates peripheral arterioles, reducing peripheral vascular resistance and blood pressure.