سعر كلودين تك 0.5 مجم 10 كبسولات 2025

Cludinetech 0.5mg 10 h.g.cap: Entecavir 0.5 mg (European Egyptian Pharm. Ind. > Pharma-Tech).

• Nucleoside analog reverse transcriptase inhibitor for chronic hepatitis B virus infection in adults (and pediatric per some labels) with evidence of active viral replication and persistent elevations in serum aminotransferases or histologically active disease (US Baraclude).Population: AdultsDailyMed (U.S. National Library of Medicine)

• Hypersensitivity to entecavir or any component.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warnings: severe acute HBV exacerbations on discontinuation; lactic acidosis / severe hepatomegaly with steatosis; HIV co-infection — may cause HIV resistance if HBV therapy given without HIV ART. Dose adjust in renal impairment.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Drugs that reduce renal function or compete for active tubular secretionMay increase serum concentrations of entecavir or the co-administered drug (US label).DailyMed (U.S. National Library of Medicine)
• Lamivudine, adefovir dipivoxil, tenofovir disoproxil fumarateNo significant interactions observed (US label).DailyMed (U.S. National Library of Medicine)

• Use in pregnancy only if clearly needed; register pregnancies where programs exist (US labeling).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Entecavir: Guanosine nucleoside analogue; the triphosphate competes with deoxyguanosine triphosphate and inhibits HBV polymerase base priming, reverse transcription of the negative strand and positive-strand HBV DNA synthesis.