سعر نيكسبرازول 40مجم 14 كبسولة ممتد المفعول 2024

Nixprazole 40 mg esomeprazole delayed-release capsules (Sigma/Hochster, Egypt), box of 14; proton pump inhibitor for acid-related disorders.

• Short-term healing of erosive esophagitisPopulation: Adults and adolescents 12-17 yearsDailyMed (U.S. National Library of Medicine)
• Maintenance of healing of erosive esophagitisPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Short-term treatment of heartburn and other symptoms of GERDPopulation: Adults and adolescents 12-17 yearsDailyMed (U.S. National Library of Medicine)

• Most common in adults (>1%): headache, diarrhoea, nausea, flatulence, abdominal pain, constipation, dry mouth.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to substituted benzimidazoles or any component (reactions include anaphylaxis, angioedema, bronchospasm, acute tubulointerstitial nephritis, urticaria); patients receiving rilpivirine-containing products.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Symptomatic response does not exclude gastric malignancy; acute tubulointerstitial nephritis; Clostridioides difficile-associated diarrhoea; bone fractures with long-term high-dose use; severe cutaneous adverse reactions; cutaneous and systemic lupus erythematosus; vitamin B12 deficiency with use over 3 years; hypomagnesaemia; raised chromogranin A interferes with neuroendocrine tumour tests (stop 14 days before); fundic gland polyps.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• ClopidogrelEsomeprazole reduces the antiplatelet activity of clopidogrel (CYP2C19 inhibition); avoid concomitant use.DailyMed (U.S. National Library of Medicine)
• Rilpivirine-containing productsContraindicated (reduced rilpivirine exposure).DailyMed (U.S. National Library of Medicine)
• St John's wort, rifampinMay decrease esomeprazole exposure; avoid concomitant use.DailyMed (U.S. National Library of Medicine)

• No adequate studies of esomeprazole in pregnant women; epidemiological data on first-trimester omeprazole use show no increased risk of major congenital malformations; no teratogenicity in animal studies with esomeprazole magnesium, but changes in bone morphology in rat offspring at high doses.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Limited data suggest omeprazole may be present in human milk; no data on effects on the breastfed infant or milk production; weigh benefits against the mother's need.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Esomeprazole: S-isomer of omeprazole; inhibits the gastric H+/K+-ATPase (proton pump) of parietal cells, suppressing basal and stimulated acid secretion (US NEXIUM label).