سعر فورتزار 100/25 مجم 8 أقراص 2022

Film-coated tablets combining losartan potassium 100 mg (angiotensin II receptor blocker) with hydrochlorothiazide 25 mg (thiazide diuretic) for hypertension.

• Hypertension, when combination therapy is appropriate; reduction of stroke risk in hypertensive patients with left ventricular hypertrophy (not shown to apply to Black patients).Population: AdultsDailyMed (U.S. NLM)
• Essential hypertension in patients whose blood pressure is not adequately controlled on losartan or hydrochlorothiazide alone.Population: Adultselectronic medicines compendium (emc)

• Contraindicated in hypersensitivity to any component, anuria or sulfonamide hypersensitivity, and co-administration with aliskiren in patients with diabetes.International label, same formulation · DailyMed (U.S. NLM)
• Also contraindicated in the second and third trimesters of pregnancy, severe hepatic or renal impairment, refractory hypokalaemia or hypercalcaemia, refractory hyponatraemia, symptomatic hyperuricaemia/gout, and with aliskiren in diabetes or renal impairment (GFR below 60).International label, same formulation · electronic medicines compendium (emc)

• Boxed warning - fetal toxicity: discontinue as soon as pregnancy is detected; drugs acting on the renin-angiotensin system can cause fetal injury and death. Also: hypotension in volume-depleted patients, impaired renal function, electrolyte imbalance, acute myopia and secondary angle-closure glaucoma (hydrochlorothiazide), possible exacerbation of systemic lupus erythematosus.International label, same formulation · DailyMed (U.S. NLM)

• AliskirenDo not co-administer with aliskiren in patients with diabetes.DailyMed (U.S. NLM)
• LithiumIncreases in serum lithium concentrations and toxicity; monitor lithium levels.DailyMed (U.S. NLM)
• NSAIDs including COX-2 inhibitorsMay reduce the antihypertensive effect and worsen renal function, especially in elderly or volume-depleted patients.DailyMed (U.S. NLM)

• Fetal toxicity: discontinue as soon as possible when pregnancy is detected.International label, same formulation · DailyMed (U.S. NLM)
• Advise women not to breastfeed during treatment, or decide whether to discontinue the drug, considering its importance to the mother (US label).International label, same formulation · DailyMed (U.S. NLM)

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