سعر رامينارت 600مجم 10 اقراص 2022

Telbivudine 600 mg film-coated tablets (10 per pack) by Rameda, Egypt; an oral nucleoside analogue for chronic hepatitis B.

• Chronic hepatitis B in adults with compensated liver disease, evidence of viral replication, persistently elevated ALT and histological active inflammation and/or fibrosisPopulation: AdultsEuropean Medicines Agency

• Hypersensitivity to telbivudine or excipients.International label, same formulation · European Medicines Agency
• Combination with pegylated or standard interferon alfa.International label, same formulation · European Medicines Agency

• Severe acute exacerbations of hepatitis B may occur during and after stopping treatment; monitor closely, especially cirrhotic patients.International label, same formulation · European Medicines Agency
• Myopathy and myalgia reported weeks to months after starting; discontinue if myopathy is diagnosed.International label, same formulation · European Medicines Agency

• Limited first-trimester data show no malformative toxicity and >1000 second/third-trimester outcomes show no fetal/neonatal toxicity; use only if benefit outweighs risk.International label, same formulation · European Medicines Agency
• Women should not breastfeed while taking telbivudine.International label, same formulation · European Medicines Agency

• Telbivudine: Phosphorylated to telbivudine triphosphate, which inhibits HBV DNA polymerase and causes chain termination.