سعر سيفيرس 10 مجم أقراص 2022

Civirus 10 mg tabs.: Adefovir (Multi-Apex).

• Treatment of chronic hepatitis B in patients 12 years of age and older (US adefovir dipivoxil tablets SPL).Population: See labelDailyMed (U.S. National Library of Medicine)

• Common adverse reactions include asthenia, headache, abdominal pain, nausea, flatulence, diarrhea, dyspepsia, and elevated creatinine (monitor).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Contraindicated in patients with previously demonstrated hypersensitivity to any component of the product.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: severe acute exacerbations of hepatitis upon discontinuation — monitor hepatic function for months after stopping; nephrotoxicity — monitor renal function and adjust dose in impairment; HIV resistance risk if used in unrecognized/untreated HIV co-infection; lactic acidosis and severe hepatomegaly with steatosis (nucleoside analogues).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Nephrotoxic agents (e.g. NSAIDs, aminoglycosides, vancomycin)May increase risk of nephrotoxicity; monitor renal function.DailyMed (U.S. National Library of Medicine)
• TenofovirRelated nucleotide; avoid unnecessary combinations — resistance and additive renal risk concerns.DailyMed (U.S. National Library of Medicine)

• Use in pregnancy only if clearly needed; insufficient human data (US labels).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Adefovir: Adefovir diphosphate inhibits HBV DNA polymerase (reverse transcriptase) by competing with deoxyadenosine triphosphate and causing DNA chain termination after incorporation.