سعر هيبافيرين 200 مجم 170 كبسولة 2022

Ribavirin 200 mg capsules, pack of 170 (Amriya).

• Chronic hepatitis C in patients 3 years and older with compensated liver disease, in combination with interferon alfa-2b (pegylated or non-pegylated); ribavirin monotherapy is not effective.Population: Adults and children >= 3 yearsDailyMed (U.S. National Library of Medicine)

• Pregnant women and men whose female partners are pregnant.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Known hypersensitivity reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis or erythema multiforme to ribavirin or any component.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Autoimmune hepatitis; haemoglobinopathies (e.g. thalassaemia major, sickle-cell anaemia); creatinine clearance < 50 mL/min; co-administration with didanosine.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: significant teratogenic/embryocidal effects in animals; avoid pregnancy and use effective contraception during therapy and for 9 months after (female patients) or 6 months after (female partners of male patients).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Boxed warning: haemolytic anaemia may worsen cardiac disease and has led to fatal and non-fatal myocardial infarction; patients with significant or unstable cardiac disease should not be treated. Ribavirin monotherapy is not effective for chronic hepatitis C.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• DidanosineContraindicated: increased exposure to the active metabolite of didanosine; fatal hepatic failure, peripheral neuropathy, pancreatitis and lactic acidosis reported.DailyMed (U.S. National Library of Medicine)

• Contraindicated in pregnant women and in men whose female partners are pregnant; animal data show teratogenic and/or embryocidal effects; ribavirin persists in intracellular compartments.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk or effects on the breastfed infant; weigh benefits of breastfeeding against maternal need and potential infant risk.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Ribavirin: Synthetic nucleoside analogue phosphorylated intracellularly; exact antiviral mechanism against HCV not fully established.