سعر تربتيزول Tryptizol‏ 10مجم 100 قرص 2026

Amitriptyline 10 mg oral tablets (Tryptizol) marketed in Egypt by Kahira; a tricyclic antidepressant.

• Cardiovascular (arrhythmias, orthostatic hypotension, heart block), CNS (drowsiness, dizziness, confusion, seizures), anticholinergic effects (dry mouth, constipation, urinary retention, blurred vision), allergic reactions and bone marrow depression have been reported.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Prior hypersensitivity to amitriptyline.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Concomitant MAO inhibitors (allow at least 14 days after stopping an MAOI); concomitant cisapride.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Acute recovery phase after myocardial infarction.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: antidepressants increased the risk of suicidal thinking and behavior in children, adolescents and young adults; monitor all patients for clinical worsening, suicidality and unusual behavior changes, especially early in treatment and at dose changes.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• MAO inhibitorsContraindicated: hyperpyretic crises, severe convulsions and deaths reported; 14-day washout.DailyMed (U.S. National Library of Medicine)
• CisaprideContraindicated because of potential QT prolongation and arrhythmia.DailyMed (U.S. National Library of Medicine)

• US label (older format): teratogenic in some animal studies at high doses; no adequate and well-controlled studies in pregnant women; use only if potential benefit justifies potential risk to the fetus.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Amitriptyline is excreted into breast milk; decide whether to discontinue nursing or the drug.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Amitriptyline: Mechanism in humans not fully known; inhibits the membrane pump mechanism responsible for neuronal uptake of norepinephrine and serotonin (US label).